Endocrine Abstracts

Introduction: Pregnancy for women with Graves’ disease is at risk for the mother and the newborn. In fact neonatal hyperthyroidism is uncommon, often transient in the context of maternal Graves’ disease (1% of children). Immediate treatment is essential for a good prognosis, prenatal treatment improves foetal and neonatal development.Case report: We report the case of a patient, known for Graves’ disease since 2006, treated initially with ...

Introduction: Disorders of sex development include a large number of congenital conditions related to unusual chromosomal sex (gonosomal abnormalities), defective testicular development, or abnormal hormone secretion or receptivity, resulting in unusual external and/or internal genitalia development rare. Patients and methods we report 3 cases of disorders of sex development 46XY reveled at adult age. clinical, biological and radiological funding are reported in the following ...

Introduction: Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are two auto-immune diseases. They have different phenotypes and are generally believed to share a number of common etiological factors but the mechanisms leading to their dichotomy are unknown. An unusual outcome of HT is the conversion to GD.A mechanism that might be hypothesized to account for the change from HT to GD is the alteration in the biological activity of TSH recep...

Introduction: Cushing’s syndrome is rare but severe because of his association with multiple complications and particularly increased cardiovascular factors. This complications determine a mortality rate four times higher than in general population.Objects: The aim of our study was to evalated the prevalence of cardiovascular factors in Cushing’ syndrome.Subjects and methods: Twenty-five patients with Cushing’ syndro...

Introduction: Adrenal myelolipoma is a rare, benign and nonfunctional tumor composed of mature adipose and hematopoietic cells. It is often of incidental finding (8%) and the diagnosis is based on radiological imaging. We report two cases of giant adrenal myelolipoma and discuss the diagnostic and therapeutic aspects of this pathology.Observation: Patient D.K 40 years old, hospitalized for adrenal mass revealed by right back pain radiating to the right h...

Background: Von Hippel–Lindau (VHL) is a rare, autosomal dominant syndrome characterized by the development of highly vascularized tumors in multiple organs. VHL affects approximately 1 in 35,000 live births. Tumors associated with VHL include hemangioblastom of the retina and central nervous system, pheochromocytomas, endolymphatic sac tumors of the middle ear, and epididymal or round ligament cysts. In 80% of patients, VHL disease is familial caused by mutations in the ...

Background: Post traumatic Hypopituitarism (PTHP) is common, its prevalence is about 30%.Aim: The aim is firstly to assess the frequency and predictive factors of hypopituitarism 3 and 12 months following Brain injury (BI) in a simple of 133 victims of moderate to severe BI in two neighbors’ hospitals in the east of Algiers. Secondly is to evaluate the quality of life and neurocognitive status of this cohort.Method: Hypopituit...

Background: Biological diagnosis of adrenal insufficiency (AI) is very difficult in the setting of critical illness like in traumatic brain injury (TBI), and the cut off defining AI need more precision.Aim: The aim is to assess the frequency and predictive factors of AI in a simple of 277 victims of moderate to severe BI in two neighbors’ hospitals in the east of Algiers.Method: Between November 2009 and December 2013, 277 pat...

Adrenal tuberculosis was first described by Thomas Addison in 1855, Isolated adrenal tuberculosis is rare and between represents 1–2% of the aetiologies of adrenal masses called expired incidentalomas. We report the case of a related Addison’s disease is a progressive adrenal tuberculosis which could benefit from exploration and a tomography monitoring on anti tuberculosis treatment. Patient aged 35 years presented himself to medical emergency with clinical surgical ...

Introduction: Pancreatic neuroendocrine tumors (PNET) are a heterogeneous group with various clinical presentations and lineage. They have an incidence of one per 100 000 individuals per year and represent about 1–2% of all pancreatic tumors. Non functional PNET (NF-PNET) are incidentally discovered in most cases. Pulmonary neuroendocrine tumors constitue a distinct category of tumors with morphologic and biologic neuroendocrine features, they present 20–30% of all N...